Kieran Fuller, Abhay Pandit and Dimitrios I. Zeugolis Pages 23 - 34 ( 12 )
The increased interest in nanotechnology has resulted in an intense investigation and development of nanofabrication methods. Among the bottom-up approaches, electro-spinning has attracted great interest in recent years. The popularity of electro-spinning lays on the fact that it is a relatively simple and economic technique that enables production of large quantities of nano- to micro-meter range fibrous materials with various morphologies and architectural features. The versatility of electro-spinning is evidenced by the range of applications being utilised, including filtration, textiles, batteries, and tissue engineering and regenerative medicine. Specifically to biomedical applications, advancements in the electro-spinning setup have allowed the development of electro-spun mats that closely imitate native extracellular matrix assemblies and provide opportunities for localised and sustained delivery of therapeutics. Herein, we are discussing different electro-spinning setups and their distinct benefits for regenerative medicine applications.
Architectural features, delivery of therapeutics/biologics, electro-spinning, nano- and micro-fibres, scaffold architecture, tissue engineering.
Network of Excellence for Functional Biomaterials (NFB), National University of Ireland Galway (NUI Galway), Galway, Ireland.