Satya Prakash Singh*, Anup Kumar Sirbaiya and Anuradha Mishra Pages 246 - 256 ( 11 )
Background: Nanoparticle technologies used for human administration must be designed to interact with living host environment. The idea about bioinspired smart drug delivery carriers includesdevelopment of biocompatible nanomaterials which can befurther loaded with drug for specific targeted drug delivery applications.
Objective: Biosmart nanosystems are used for several applications in delivery of drugs and pharmaceuticals for their therapeutic applications like biological markers, diagnostic purposes such as imaging applications and also for gene therapy. Thus the bioinspired nanocarriers are capable of carrying biologically active molecules to the target sites. This bioinspired nanosystems, constitutes of lipids, polymers and biomaterials which utilizes various responsive sensors for targeted drug delivery systems. However, external conditions such as heat, light, magnetic or electric field and ultrasounds, alongwith temperature, altered pH and ionic strength can affect the bioinspired smart nanosystem for drug delivery.
Conclusion: The present review focuses on challengesfor development of bioinspired smart nanocarriers for management of various disorders.
Biosmart drug delivery systems, endogenous stimuli, exogenous stimuli, multiresponsive, thermoresponsive, Nanosystems.
Department of Pharmaceutics, Faculty of Pharmacy, Integral University, Lucknow-226026, U.P., Department of Pharmaceutics, Faculty of Pharmacy, Integral University, Lucknow-226026, U.P., Department of Pharmaceutics, Faculty of Pharmacy, Integral University, Lucknow-226026, U.P.